Automated solutions to multi-channel signal enhancement for improving speech communication in noisy environments has become a popular goal among the research community. Many proposed approaches focus on adapting to speech signals based on their temporal characteristics but these methods are primarily limited to specific types of desired and undesired sound sources. This paper outlines a new method to adapt to desired and undesired signals using their spatial statistics, independent of their temporal characteristics. The method uses a linearly constrained minimum variance (LCMV) beamformer to estimate the relative source contribution of each source in a mixture, which is then used to weight statistical estimates of the spatial characteristics of each source used for final separation. The proposed method allows for instantaneous desired and undesired source selection, a useful ability for the enhancement of conversations. The simulated results show that the method can adapt to the targeted source in noisy mixture signals and that under realistic conditions it is also capable of reaching ideal MVDR performance.